Open Clinical Trial Data for All? A View from Regulators

Open Clinical Trial Data for All? A View from Regulators

In this issue of PLoS Medicine, Doshi and colleagues argue that the full clinical trial reports of authorized drugs should be made publicly available to enable independent re-analysis of drugs’ benefits and risks [1]. We offer comments on their call for openness from a European Union drug regulatory perspective. For the purpose of this discussion, we consider ‘‘clinical study reports’’ to compr...

Community mining of open clinical trial data

UK Parliament calls for sharing of all clinical trial data.

Barriers to open data release: A view from the top

The pressure for governments to release much of the vast reservoirs of data that they hold continues to grow. This pressure is grounded not just in principles such as the right of the public to know or freedom of information, but in beliefs, what have even been called myths, about the economic, social, administrative and political benefits that will flow from the wide availability of such data....

Clinical Outcomes of Open versus Arthroscopic Surgery for Lateral Epicondylitis, Evidence from a Systematic Review

Background: Lateral epicondylitis (LE) also known as tennis elbow is a common disease of middle-aged population.Surgery is a treatment of choice in patients not responded to the conservative management. Open and arthroscopicrelease are the two main choices for LE surgery; however, an overall consensus is not available. This study was aimedto compare the clinical outcomes after conventional open...